Supplementary Datasets for dadasnake workflow

This dataset contains configuration and results files for the proof-of-principle of the dadasnake pipeline. Includes tables with the composition of ground-truth data or mock-communities.

dadasnake wraps pre-processing of sequencing reads, delineation of exact sequencing variants using the favorably benchmarked, widely-used the DADA2 algorithm, taxonomic classification and post-processing of the resultant tables, and hand-off in standard formats, into a user-friendly, one-command Snakemake pipeline. The suitability of the provided default configurations is demonstrated using mock-community data from bacteria and archaea, as well as fungi. By use of Snakemake, dadasnake makes efficient use of high-performance computing infrastructures. Easy user configuration guarantees flexibility of all steps, including the processing of data from multiple sequencing platforms. dadasnake facilitates easy installation via conda environments. dadasnake is available at https://github.com/a-h-b/dadasnake .