Published October 3, 2020
| Version 1.0
Software
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SHARC
Creators
Description
SHARC is a pipeline for somatic SV calling and filtering from tumor-only Nanopore sequencing data. It performs mapping, SV calling, SV filtering, random forest classification, blacklist filtering and SV prioritization, followed by automated primer design for PCR amplicons of 80-120 bp that are useful to track cancer ctDNA molecules in liquid biopsies. We provide packages to run on:
- SLURM cluster
- SGE cluster
- Local
- Singularity image
- Docker image