Journal article Open Access

EVALUATION OF ISOLATED PHYTOSTEROL FROM LEAVES OF HOLOPTELEA INTEGRIFOLIA (ROXB.) PLANCH FOR IT'S ANTIDEPRESSANT ACTIVITY IN EXPERIMENTAL ANIMALS

Ravindra C. Sutar*

Background: Majority of scientific documentation suggested prominent role of Phytosterols towards Antidepressant activity. The main objective of the work was to evaluate Antidepressant activity of Holoptelea integrifolia isolated Phytosterol (HIIP) from petroleum ether extract (PEHI) of leaves of Holoptelea integrifolia (Roxb) Planch. Methods: The Antidepressant activity of different doses of HIIP (10 and 30 mg/kg-p.o.) was evaluated using Forced Swim Test (FST) in mice. Results: HIIP-30 mg/kg was more potent than HIIP-10 mg/kg for showing Antidepressant activity. Conclusions: The results indicate that HIIP shows Antidepressant activity which was dose dependent.

Files (849.6 kB)
Name Size
190602.pdf
md5:ccacf3f3fee2e690c55810e01a4edfb1
849.6 kB Download
24
11
views
downloads
All versions This version
Views 2424
Downloads 1111
Data volume 9.3 MB9.3 MB
Unique views 2424
Unique downloads 1111

Share

Cite as