ROLE OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR IN THROMBOLYSIS
Description
Stroke or cerebrovascular accident is the sudden interruption of blood supply to brain, which is a medical
emergency condition, and prompt treatment is crucial or may lead to fatal conditions or lifelong disability.
Intravenous Tissue Plasminogen Activator (t-PA) was recognised and approved as the thrombolytic agent
for acute ischemic stroke that can improve patient outcome and resolve neurological deficit. Apart from
stroke, t-PA showed effectiveness in treating Myocardial infarction, venous thromboembolism etc. This
article review regarding role of t-PA in thrombolysis provide an in-depth understanding of the role of Tissue
Plasminogen Activator as thrombolytic agent in stroke and other conditions like Myocardial infarction,
Thromboembolism.