Published August 13, 2020 | Version 1.0.0
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Flow Magnetic Tweezers: Gyrase dynamics in absence of drug Ciprofloxacin

Authors/Creators

  • 1. Max Planck Institite of Biochemistry

Description

The video contains a whole field from a force spectroscopy experiment called Flow Magnetic Tweezers (FMT). It shows E. coli DNA Gyrase manipulating DNA topology by relaxing positive and introducing negative coils in absence of Ciprofloxacin, reaction of Gyrase to external torque and eventual wash with SDS.

Files

FMT_Gyrase_NoCipro.zip

Files (49.9 GB)

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md5:75262e8a718b6c039f07607fd69f9a6b
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Additional details

Funding

European Commission
REPLISOMEBYPASS - Challenges on the road to genome duplication: Single-molecule approaches to study replisome collisions 804098