Eradicate Coronavirus by blocking replication, counteracting its defense system

SIRT1 inhibitors can reduce replication of many viruses with certain similar characteristics to those of Coronaviruses, while p53 protein is another important factor in down-regulation of growth. There are some molecules that inhibit Sirtuin 1 and 2, in addition to activate p53 protein, by means of regulation of the interactions used by Coronaviruses as self-defense mechanism. By blocking virus growth and continuous replication, associating the already tested Antiviral medicines, Covid-19 could be eradicated.