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Preprint Open Access

Eradicate Coronavirus by blocking replication, counteracting its defense system

Kira Smith

SIRT1 inhibitors can reduce replication of many viruses with certain similar characteristics to those of Coronaviruses, while p53 protein is another important factor in down-regulation of growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activate p53 protein, by means of regulation of the interactions used by Coronaviruses as self-defense mechanism. By blocking virus growth and continuous replication, associating the already tested Antiviral medicines, Covid-19 can be definitively eradicated.

Created and uploaded on Academia.edu on March 2020.
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