Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho
Creators
- 1. Swiss Tropical and Public Health Institute, Basel, Switzerland
- 2. SolidarMed, Partnerships for Health, Lesotho
- 3. Motebang Government Hospital, Leribe, LesothoTilo
- 4. Senkatana HIV Clinic, Maseru, Lesotho
- 5. Department of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
- 6. Molecular Virology, Department of Biomedicine, University of Basel, Basel, Switzerland
Description
These are pseudo-anonymised data from the SESOTHO randomised trial: "Switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL – a multicenter, parallel-group, open-label, randomized clinical study in rural Lesotho". There are two datasets, one containing baseline data (one row per participant) and one containing longitudinal viral load data (one row per participant per visit). The data dictionary explains the data available in each dataset. Between August 2017 and August 2019, 80 eligible and consenting participants were enrolled from eight health facilities in four districts of Lesotho, and followed up for nine months. The protocol was published, DOI: 10.1186/s12879-018-2979-y
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Additional details
Related works
- Cites
- Journal article: 10.1186/s12879-018-2979-y (DOI)
Funding
- Improving the HIV care cascade in Lesotho: Towards 90-90-90 - A research collaboration with the Ministry of Health IZ07Z0_160876
- Swiss National Science Foundation
- Evidence-based Differentiated Care for HIV in South-Eastern Africa: Shaping the post 2020 agenda PCEFP3_181355
- Swiss National Science Foundation
- Supporting Lesotho on the way towards the UNAIDS 90-90-90 targets: Operational and clinical research addressing HIV/AIDS care in resource-limited settings 323530_177576
- Swiss National Science Foundation