Published November 30, 2013 | Version v1
Journal article Open

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

Description

Whole-genome sequences of two novel SARS-CoV-related bat coronaviruses, in addition to a live isolate of a bat SARS-like coronavirus, are reported; the live isolate can infect human cells using ACE2, providing the strongest evidence to date that Chinese horseshoe bats are natural reservoirs of SARS-CoV.

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Nature.503.535–538.pdf

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Additional details

Biodiversity

Host of
(Rhinolophus sinicus, Chinese horseshoe bats) → (SL-CoV Rs3367)
(Rhinolophus sinicus, Chinese horseshoe bats) → (SL-CoV RsSHC014)
(Rhinolophus sinicus, Chinese horseshoe bats) → (SL-CoV-WIV1)
(pig) → (SL-CoV-WIV1)