Journal article Open Access

Time to make a change: A call for more experimental research on key mechanisms in anorexia nervosa

Glashouwer, Klaske A.; Brockmeyer, Timo; Cardi, Valentina; Jansen, Anita; Murray, Stuart B.; Blechert, Jens; Levinson, Cheri A.; Schmidt, Ulrike; Tchanturia, Kate; Wade, Tracey D.; Svaldi, Jennifer; Giel, Katrin E.; Favaro, Angela; Fernández-Aranda, Fernando; Friederich, Hans-Christoph; Naumann, Eva; Treasure, Janet L.; Tuschen-Caffier, Brunna; Vocks, Silke; Werthmann, Jessica

Anorexia nervosa (AN) is a life‐threatening eating disorder, characterised by persistent pathological weight loss behaviours and an intense fear of weight gain and food consumption. Although there is an abundance of scientific theories on the neurobiological, psychological and sociocultural factors thought to be involved in the maintenance of AN, there is little experimental research testing these ideas. The need for theory firmly grounded in empirical evidence becomes strikingly clear when we consider that current treatments for patients with AN are limited in their effectiveness, and relapse after treatment is common.

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