Published July 4, 2020 | Version v1
Journal article Open

EFFECT AND SAFETY OF PROBIOTICS TO REDUCE THE INCIDENCE OF ATOPIC DERMATITIS

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This systematic review aims to determine the effect and safety of probiotics in reducing the incidence of Atopic Dermatitis, from the pre/ post-natal period in infants and children or adults, with the most studied and effective probiotics that belong to the genera Bifidobacterium and Lactobacillus. This study was carried out, through the collection of several scientific articles between the years 2014 to 2019, with the duration of research between September 2019 to June 2020.

Atopic dermatitis is a chronic or recurrent inflammatory skin disease, characterized by dry skin, intense itching, recurrent eczematous lesions and loss of sleep.

The use of probiotics is considered a new therapeutic strategy for the treatment of this atopy. Probiotics are "live microorganisms that confer health benefits to the host when administered in adequate amounts". This produces beneficial effects, when administered in adequate quantities, having a role in the gastrointestinal tract and in the intestine-brain-skin axis and, activating several immunological mechanisms, once that the response is exacerbated in the atopic individual. Therefore, the results demonstrate efficacy, efficiency and safety in reducing the incidence of atopy. However, heterogeneity and other factors influence the atopic dermatitis score values and further studies are needed.

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References

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