Chemical composition, antimicrobial and antioxidant activities of the essential oils of three Uzbek Lamiaceae species

Mamadalieva NZ, Youssef FS, Ashour ML, Sasmakov SA, Tiezzi A, Azimova SS (2018). Chemical composition and biological activities of the essential oils from some Lamiaceae species. NATURAL PRODUCT RESEARCH, p. 1-4, ISSN: 1478-6419, doi: 10.1080/14786419.2018.1443088

The chemical composition of the essential oil from the aerial parts of three Lamiaceae species from Uzbekistan was investigated by GCMS analysis. β-Linalool (26.6%), α-terpineol (10.0%), coumarin (8.9%) and 4,5,7,7α-tetrahydro-4,4,7α-trimethyl-2(6H)-benzofuranone (5.4%) resulted as the main components of Ajuga turkestanica essential oil, while camphene (17.1%), 1,8-cineole (15.9%), β-cymene (7.9%) and limonene (7.4%) in Phlomis regelii. The essential oil of Thymus seravschanicus was dominated by thymol (37.5%), phellandral (26.0%), τ-terpinene (6.6%) and β-cymene (5.2%). The essential oils had considerable antimicrobial activity against different bacterial strains and fungi. Among the tested samples of essential oils, P. regelii essential oil has the significant antioxidant activity with IC50 value of 117.8 ± 8.02 μg/mL.