REVIEW STUDY: METFORMIN AND TYPE 2 DM PREVENTION
Description
Background: Metformin is considered as the main antidiabetic medicine which has been appeared to improve anticipation of T2DM patients as an essential end-point for prevention of diabetes.
Objective: This study aimed at providing an update on the effect of metformin in prevention of T2DM.
Methods: The online medical database was searched then the English articles from 2009 – 2020 were included in the review.
Results: There were 36 studies involved concentrating on the prevention effect of metformin on type 2 diabetes mellitus.
Conclusion: many studies propose that metformin is an active, tolerable, cheap, and cost-saving interference that can inhibit or prevent development of diabetes. Most of the metformin studies showed that metformin is not used in real-world settings. Thus, metformin needs more evidence-based treatment studies among high risk patients to evaluate its advantage in prevention or delay of diabetes and assessing its side effects and long-term effects.
Keywords: metformin, type 2 diabetes mellitus (T2DM), prevention, delay, prediabetes.