Journal article Open Access
Mr. Siddu K Mavintop, Mrs. Aisha Khanum, Ms. Ayesha Syed
Fungal infections are most commonly occurring nowadays. Out of all fungal infections, cutaneous fungal infections are the most widespread. Currently available conventional dosage forms although they are able to treat these infections, they come with some drawbacks such as poor skin permeation of drugs and high dosing frequency which leads to reduction in effectiveness against these fungal infections. Present review highlights on different types of superficial fungal infections, their causative agent, drawbacks in conventional dosage forms. It also briefs different classes of antifungal drugs, their mechanism of action with some examples of each class. It emphasizes on different novel techniques of antifungal drugs, their advantages and disadvantages. Details of each novel technique with reference to fungal infection is focussed. This review concludes various different techniques to overcome the drawbacks and to increase the effectiveness of antifungal drugs using various novel strategies.