Institut za onkologiju i radiologiju Srbije / Institute for Oncology and Radiology of Serbia
Published March 25, 2017 | Version 1.0
Journal article Open

In vitro investigation of electrophoretically deposited bioactive 2 hydroxyapatite/chitosan coatings reinforced by graphene

Authors/Creators

  • 1. Institute for Technology of Nuclear and Other Mineral Raw Materials, Bulevar Franš d'Eperea 86, 11000 Belgrade, Serbia
  • 2. Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11 000 Belgrade, Serbia
  • 3. Institute of Oncology and Radiology of Serbia, Pasterova 14, 11 000 Belgrade, Serbia
  • 4. Department of Q2 Mechanical Engineering, Kyung Hee University, Yongin 449-701 South Korea
  • 5. Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11 000 Belgrade, Serbia and Department of Q2 Mechanical Engineering, Kyung Hee University, Yongin 449-701 South Korea
  • 6. Department of Chemistry Inha University, Incheon 402751, South Korea

Description

Graphene (Gr) and natural polymer chitosan (CS) were introduced to hydroxyapatite (HAP) to produce a three-component composite coating, which was fabricated by cathodic electrophoretic deposition on Ti substrates in an ethanol suspension. These HAP/CS/Gr coatings were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS) and electrochemical measurements and found that the graphene into HAP/CS composites significantly improves their morphology, thermal stability, and bioactivity. Both HAP/CS and HAP/CS/Gr composite coatings are classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC), while antibacterial activity Q5 against Staphylococcus aureus and Escherichia coli could not be verified.

Notes

This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) by the Ministry of Education, Science and Technology (project number: 2016R1A2B4016034) and Ministry of Education, Science and Technological Development, Republic of Serbia (Grant No. III 702 45019).

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Related works

Is source of
Journal article: 1226-086X (ISSN)

Funding

Ministry of Education, Science and Technological Development
Synthesis, processing and applications of nanostructured multifunctional materials with defined properties 45019