Published September 3, 2020 | Version v1

Epigenome-Wide Association Study of DNA Methylation and Adult Asthma in the Agricultural Lung Health Study

Authors/Creators

  • 1. NIEHS

Description

In an epigenome-wide association study of blood DNA methylation in adults conducted in the Agricultural Lung Health Study, 524 differentially methylated CpG sites were associated with non-atopic asthma (FDR<0.05) and 1,086 differentially methylated CpGs were associated with atopic asthma. No CpG sites were differentially methylated in relation to atopy alone. 

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ALHS_AtopicAsthma_EWAS_817235x1830_FULL_RESULTS.csv

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Is cited by
Journal article: 10.1183/13993003.00217-2020 (DOI)

References

  • Hoang TT, Sikdar S, Xu C-J, et al. Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study. Eur Respir J 2020; 0: 2000217.