Coronavirus Disease Research Community - COVID-19
Published January 31, 2020 | Version v3
Dataset Open

Genome-wide structure and function modeling of SARS-COV-2

Authors/Creators

  • 1. University of Michigan

Description

Homology models and function annotation for all proteins in the SARS-CoV-2 genome. For a description of each file, follow this link. 

Files

models (1).zip

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Additional details

Related works

Is derived from
https://zhanglab.ccmb.med.umich.edu/COVID-19/ (URL)
References
10.1101/2020.03.28.013607 (DOI)
10.1021/acs.jproteome.0c00129 (DOI)

References

  • Chengxin Zhang, Wei Zheng, Xiaoqiang Huang, Eric W. Bell, Xiaogen Zhou, Yang Zhang (2020) Protein structure and sequence re-analysis of 2019-nCoV genome refutes snakes as its intermediate host and the unique similarity between its spike protein insertions and HIV-1. Journal of Proteome Research. 19: 1351-1360, 2020
  • Xiaoqiang Huang, Robin Pearcs, Yang Zhang. Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2. BioRxiv Prinprint doi: https://doi.org/10.1101/2020.03.28.013607