Published April 17, 2020 | Version v1
Dataset Open

MOSTWAS models, TWAS summary statistics, and simulation results for Bhattacharya and Love, 2020

Authors/Creators

  • 1. Department of Biostatistics, University of North Carolina at Chapel Hill
  • 2. Department of Biostatistics, Department of Genetics, University of North Carolina at Chapel Hill

Description

This compressed folder contains three sub-folders that all pertain to models and results generated with Multi-Omic Strategies for Transcriptome-Wide Association Studies (MOSTWAS):

  1. MOSTWAS_Models contains compressed folders for MOSTWAS models trains on TCGA breast cancer and ROS/MAP pre-frontal cortex multi-omic data.
  2. Simulations contains Simulation_Results_MOSTWAS.xlsx that provides full simulation results outlined in Bhattacharya and Love, 2020 (paper accompanying MOSTWAS).
  3. TWAS_associations contains four Excel files that provide MOSTWAS and local-only TWAS associations for breast cancer-specific survival (using iCOGs GWAS summary statistics), late-onset Alzheimer's disease risk (using IGAP GWAS summary statistics), and major depressive disorder risk (using PGC GWAS and UK Biobank GWAX summary statistics).

Files

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