Co-morbid Psychiatric Disorders in Patients with Irritable Bowel Syndrome Attending Gastroenterology and Psychiatry OPD in Tertiary Centre

Background: Irritable bowel syndrome [IBS] is a chronic psycho-physiological disorder. It is considered to be the most common functional gastrointestinal disorder, and about 50-90% of IBS patients have associated psychiatric co-morbidity. Aim and Objectives: To assess and compare the socio-demographic profile and co-occurring of the psychiatric co-morbidity between the groups of patients with IBS and health controls. Methods and materials: A Cross sectional comparative study was conducted during the period of June 2017 to May 2018. A total of 100 individuals (50 patients with IBS and 50 health controls) who fulfilled the inclusion and exclusion criteria were interviewed using a semi-structured interview schedule consisting of socio-demographic profile, Rome IV criteria to assess Symptoms and severity of irritable bowel syndrome, the Mini screen, PHQ-15,HAM-D, and HAM-A. The ICD-10 diagnostic criterion was used for the psychiatric disorder. The statistical test such mean, SD, and Chi-squire test and t-test were used to compare the groups. The data was analyzed using SPSS IBM version 23 software. Results: Mean age of our patients with IBS and healthy controls was 30.30±10.570 and 27.28±8.887 years, respectively. Males outnumbered females in our cases as well as their controls. There were common psychiatric disorders such as major depression, generalized anxiety disorders and mixed depression, social phobia, agora phobia, OCD, panic disorder and anorexia nervosa especially among patient with IBS. Co-occurrence of psychiatric disorders especially major depression, GAD, and mixed depression-anxiety was found significantly high (p<0.05) among patient with IBS compared to the healthy controls. Conclusions: Majority of the patient with IBS were found with psychiatric co-morbidity compared to the health controls.