Published April 7, 2020 | Version v1
Dataset Restricted

Immunogenomics of colorectal cancer response to immune checkpoint blockade: Imaging Mass Cytometry

Creators

  • 1. Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE11UL, UK
  • 2. Biomedical Research Centre, Guy's and St. Thomas' NHS Trust, London SE1 9RT, UK
  • 3. Advanced Sequencing Facility, the Francis Crick Institute, London NW1 1AT, UK
  • 4. Cancer Evolution and Genome Instability Laboratory Francis Crick Institute, London NW1 1AT, UK; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, London WC1E 6DD, UK
  • 5. School of Immunology and Microbial Sciences, King's College London, London SE1 9RT, UK
  • 6. FASTBASE Solutions S.L, Astondo bidea, Kabi 612 Scientific and Technology Park of Bizkaia 48160 Derio, Spain
  • 7. FASTBASE Solutions, Scientific and Technology Park 48160 Derio, Spain ; Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK
  • 8. Protein Phosphorylation Laboratory, Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE11UL, UK
  • 9. Department of Histopathology, University College London Cancer Institute, London WC1E 6JJ, UK
  • 10. University College London NHS Foundation Trust, London NW1 2PG, UK

Description

Immunogenomics of colorectal cancer response to immune checkpoint blockade

Imaging Mass Cytometry data supporting the paper: "Immunogenomics of colorectal cancer response to immune checkpoint blockade"

The provided data includes:

  • Sample metadata: Raw_txt_mcd_files.tar.gz/Metadata.csv
  • Raw ablation data in .mcd or .txt format: Raw_txt_mcd_files.tar.gz
  • Thresholded and cleaned tiff images:Cleaned_Tiff_Images.tar.gz
  • Tissue/tumor/stroma masks: Masks.tar.gz
  • Single-cell marker expression values and centroid coordinates: Single_Cell_Data.csv

Files

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The restriction is only for tracking and logging purposes, access will be granted upon request. Please write your name and affiliations to the following email addresses:
francesca.ciccarelli@kcl.ac.uk
michele.bortolomeazzi@kcl.ac.uk

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