Published February 23, 2020 | Version v1

WHEN THE LARYNX PLEADS THE THYROID

  • 1. Department of Endocrinology, Diabetology and Nutrition, Military Hospital Moulay Ismail, Meknes, Morocco.
  • 2. University Sidi Mohamed Ben Abdellah, Faculty of Medicine and Pharmacy, Fez, Morocco.
  • 3. University Mohammed V, Faculty of Medicine and Pharmacy, Rabat, Morocco.

Description

We related the case of medullary thyroid carcinoma, revealed by multiple inaugural pharyngolaryngeal metastases, requiring the use of a rescue tracheotomy. Their histopathology confirmed by laryngeal biopsy performed during a panendoscopy of the upper aero-digestive tract. Following the exclusion of remote metastases by positron emission tomography scan, a mutation of the RET proto-oncogene was investigated, allowing the family nature of the carcinoma to be excluded. The patient received an external radiotherapy with a palliative aim in front of the inextricable character of the tumor. Therapeutic modalities of this rare form of pharyngolaryngeal localization of medullary thyroid carcinoma are discussed.

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