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CORBEL Assessment of animal model phenotypes against outcome measures

Nicola Harman; Adrian Sanz-Moreno; Patricia da Silva-Buttkus; Serena Battaglia

Animal models play a crucial role in understanding the mechanisms of diseases and symptoms, and to test the efficacy and safety of treatments before conducting clinical trials. Selecting human diseases and developing core sets of clinical outcome measures as well as complementary sets of mouse phenotyping measures will contribute to narrow the gap between animal models and human trials.

The overall objective of the CORBEL task 3.2 is to promote convergence between outcome measures used for clinical trials in humans and phenotyping techniques used for testing treatments in animal models.

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