Published February 18, 2020 | Version v1
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SYNTHESIS OF AMIDES BY ACTIVATION OF CARBOXYLIC ACIDS USING PHOSPHONITRILIC CHLORIDE

  • 1. Department of Chemistry, S.G.B. College, Purna (Jn.), Dist. Parbhani (M.S.), India.

Description

A practical and efficient method has developed for the amidation of carboxylic acids using phosphonitrilic chloride trimer (PNT). We identified PNT for these transformations as an effective one pot procedure. The method is suitable alternative to traditional amidation. A variety of useful amides were prepared. Aromatic as well as aliphatic carboxylic acids have been reacted converted into corresponding amides in excellent yields.

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