Published February 11, 2020 | Version v1
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GSAn_Supplementary_Data: Description of the investigated gene sets

Description

The following table provides the number of genes in each BTM gene set [1] as well as the number of genes annotated within GOA and by each of the following tools: GSAn, DAVID [2], g:Profiler [3], ClusterProfiler [4] and WebGestalt [5].

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References

  • [1] Li S., Rouphael N., Duraisingham S., Romero-Steiner S., Presnell S., Davis C., Schmidt D.S., Johnson S.E., Milton A., Rajam G., et al . Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nature Immunology , 2013;15:195{204. doi:10.1038/ni.2789
  • [2] Huang D.W., Sherman B.T., Tan Q., Collins J.R., Alvord W.G., Roayaei J., Stephens R., Baseler M.W., Lane H.C., and Lempicki R.A. The DAVID gene functional classication tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biology , 2007;8(9):R183. doi:10.1186/gb-2007-8-9-r183
  • [3] Reimand J., Kull M., Peterson H., Hansen J., and Vilo J. g:Profiler a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Research , 2007;35(suppl 2):W193{W200. doi:10.1093/nar/gkm22
  • [4] Yu G., Wang L., Han Y., and He Q. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS , 2012;16(5):284{287. doi:10.1089/omi.2011.0118
  • [5] Zhang B., Kirov S., and Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Research , 2005;33(suppl 2):W741{W748. doi:10.1093/nar/gki475