Dataset Open Access

Data from Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione

Beáta Lizák; Julia Birk; Melinda Zana; Gergely Kosztyi; Denise V. Kratschmar; Alex Odermatt; Richard Zimmermann; Miklós Geiszt; Christian Appenzeller-Herzog; Gábor Bánhegyi

Research data associated with the manuscript "Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione" that is under consideration at BMC Biology.

Data files are associated with eight main figures and four supplementary figures in the paper. For data reuse and file naming convention, note the read me.txt file.

Files (63.7 MB)
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Fig1A_roGFPlive_TG_control_20130809.csv
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Fig1B_roGFPlive_TG_BSO_20130809.csv
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Fig1C_glutathione assay_control_BSO_2013.csv
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Fig2_roGFPcytolive_TG_BCNU_20130812.csv
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Fig3A_micrograph_BCECF_digitonin_2013.tif
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Fig3B_HyPerlive_digitonin_TG_2013.csv
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Fig3C_HyPerlive_digitonin_Puro_2013.csv
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Fig4B_roGFPplate_control_TG_CsA_20140121.csv
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Fig4C_autoradiography sCGrx1p_control_TG_CsA_20140113.tif
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Fig5A_roGFPlive_TG_control_20131112.csv
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Fig5B_roGFPlive_TG_BAPTA_20131112.csv
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Fig6A1_roGFPlive_CsA_control_20131002.csv
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Fig6A2_roGFPlive_CsA_BSO_20131002.csv
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Fig6B1_roGFPlive_FK506_control_20131030.csv
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Fig6B2_roGFPlive_FK506_BSO_20131030.csv
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Fig6C_roGFPlive_CM_20131106.csv
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Fig6D1_roGFPlive_CsA_sicontrol_20131216.csv
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Fig6D2_roGFPlive_CsA_siCypA_20131216.csv
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Fig6D3_roGFPlive_CsA_siCypB_20131216.csv
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Fig7A_roGFPlive_Puro_control_20130814.csv
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Fig7B_roGFPlive_Puro_Aniso_20130814.csv
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Fig7C_roGFPlive_Puro_BSO_20130826.csv
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Fig7D1_roGFPlive_TG_sicontrol_20130822.csv
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Fig7D2_roGFPlive_TG_sisec61_20130822.csv
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Fig7D3_Western_Sec61_BiP_Actin_20130809.tif
md5:d7e6712b679f7a51434cd9fda7abaef9 		3.2 MB Download
Fig7E_roGFPlive_TG_Aniso_20130817.csv
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Fig7F1_roGFPlive_PuroTG_20130826.csv
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Fig7F2_roGFPlive_TGPuro_20130823.csv
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Fig8_1_roGFPlive_TG_wt_20191107.csv
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Fig8_2_roGFPlive_TG_KO_20191107.csv
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Fig8_3_roGFPlive_Puro_wt_20191128.csv
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Fig8_4_roGFPlive_Puro_KO_20191128.csv
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Fig8_5_roGFPlive_CsA_wt_20191121.csv
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Fig8_6_roGFPlive_CsA_KO_20191121.csv
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FigS1A_cellomicsMitoSOX_20190117.csv
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FigS1B_cellomicsMitoTracker_20190229.csv
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FigS1C_OCRcourse_DMSO_Puro_CsA_TG_2019.csv
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FigS2_1_micrograph_DMSO_Calnexin_20190207.tif
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FigS2_1_micrograph_DMSO_HA_20190207.tif
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FigS2_1_micrograph_DMSO_Hoechst_20190207.tif
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FigS2_2_micrograph_TG_Calnexin_20190207.tif
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FigS2_2_micrograph_TG_HA_20190207.tif
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FigS2_2_micrograph_TG_Hoechst_20190207.tif
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FigS2_3_micrograph_CsA_Calnexin_20190207.tif
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FigS2_3_micrograph_CsA_HA_20190207.tif
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FigS2_3_micrograph_CsA_Hoechst_20190207.tif
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FigS2_4_micrograph_Puro_Calnexin_20190207.tif
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FigS2_4_micrograph_Puro_HA_20190207.tif
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FigS2_4_micrograph_Puro_Hoechst_20190207.tif
md5:7e46e2505facdd9c3281604b2996b227 		4.4 MB Download
FigS3_HyPerlive_BSO_TG_2013.csv
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FigS4A_Western_BiP_Actin_20130814.tif
md5:d15eb6fba3f39d24126ee038eb85abc8 		3.2 MB Download
FigS4B_Western_BiP_Actin_20130814.tif
md5:82582e701679c0bdec0e455aeb00994a 		3.2 MB Download
FigS4C1_roGFPlive_CsA_subABmut_20131017.csv
md5:f5d18af734c3c9cf4e5b0e2552c2356d 		12.0 kB Download
FigS4C2_roGFPlive_CsA_subAB_20131017.csv
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FigS4C3_roGFPlive_CsA_sicontrol_20131017.csv
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FigS4C4_roGFPlive_CsA_siBip_20131017.csv
md5:212064a063095ba19709300aad85ad1b 		12.0 kB Download
Read me.txt
md5:6c245b384dbf98eddcc4dbd4bd4860f4 		1.3 kB Download
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Publication date:
February 6, 2020
DOI:
10.5281/zenodo.3648401

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Keyword(s):
endoplasmic reticulum endoplasmic reticulum stress redox homeostasis glutathione calcium Sec61 translocon cyclosporine A cyclophilins calreticulin membrane transport proteins
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