Recombination and aneuploidy data for: Insights about variation in meiosis from 31,228 human sperm genomes
Creators
- 1. Department of Genetics, Harvard Medical School; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard
Description
This repository holds crossover and aneuploidy data for 31,228 human sperm genomes sequenced with Sperm-seq. Data are described in the preprint/paper "Insights about variation in meiosis from 31,228 human sperm genomes." Several levels of data are available, e.g., each crossover (allcrossovers_hg38.txt.gz) and the numbers of crossovers detected per sperm cell (numbercrossoverspercell.txt.gz). Each data file is described in its own readme, so README_allgainsdivisionoforigin.txt explains the data present in allgainsdivisionoforigin.txt. All files are either text files or text files compressed via gzip. All data was generated as described in the preprint/paper, using scripts available in the companion repository (most recent version DOI: 10.5281/zenodo.3561080).
This new version has updated sex chromosome ploidies after identifying a minor coding error affecting ~24 cells (sexchromosomeploidy.txt.gz) and includes more detail about possible crossover error modes (README_allcrossovers_hg38.txt.gz).
Files
allgainsdivisionoforigin.txt
Files
(17.3 MB)
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Additional details
Related works
- Is supplement to
- https://www.biorxiv.org/content/10.1101/625202v1 (URL)
- References
- 10.5281/zenodo.2581596 (DOI)