Published November 1, 2019 | Version v1

Investigating The Anti-Bacterial Effects Of Mentha Longifolia Encapsulated In G2 Dendrimer On Staphylococcus Aureus And Escherichia Coli Bacterium

  • 1. aDepartment of Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Description

Regarding the recent developments in nanotechnology and tendency to use natural preservatives, the aim of this research was to determine the chemical compositions and antimicrobial effects of mentha longifolia essential oils encapsulated in G2 dendrimer against Staphylococcus aureus and Escherichia coli bacterium. In this research, G2 dendrimer nanoparticles as a new generation of dendrimers was synthesized and conjugated with mentha longifolia essential oils. The essential oils of mentha longifolia were soaked and prepared by Clevenger and after drying encapsulated into G2 dendrimer. Its compounds were determined by GC-Mass spectroscopy, and then the antimicrobial effects of mentha longifolia- G2 dendrimer mixture were studied on a gram-positive bacterium, Staphylococcus aureus and a gram negative bacteria, Escherichia coli. The results obtained from   MIC, DLS, and FTIR analysis showed that mentha longifolia- G2 dendrimer nano-composition is a new structural construct that has high usability and has strong antimicrobial effect on Staphylococcus aureus and of Escherichia coli bacterium.

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