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Published November 12, 2019 | Version v1
Dataset Open

Responses to axonal current injection in cortical layer 5 pyramidal neurons

  • 1. Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA

Contributors

  • 1. Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA

Description

Patch-clamp recordings in cortical layer 5 pyramidal neurons performed by Wenqin Hu. A current pulse is either injected in the soma or in an axonal bleb and recorded simultaneously in the axonal bleb or the soma, respectively.

The data are related to figure 7 of the paper: Hu, W., & Bean, B. P. (2018). Differential control of axonal and somatic resting potential by voltage-dependent conductances in cortical layer 5 pyramidal neurons. Neuron97(6), 1315-1326.

 

Notes

Each file corresponds to recordings in one cell. The soma-to-axonal bleb distance is written in the file name. To read and plot data there is a Python script: read_and_plot_data.py Funding: this work was supported by NINDS R01NS036855.

Files

Files (1.0 GB)

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Additional details

Related works

Is derived from
Journal article: 10.1016/j.neuron.2018.02.016 (DOI)
Is referenced by
Journal article: 10.1101/834671 (DOI)

References

  • Hu, W., & Bean, B. P. (2018). Differential control of axonal and somatic resting potential by voltage-dependent conductances in cortical layer 5 pyramidal neurons. Neuron, 97(6), 1315-1326.
  • Goethals, S., & Brette, R. (2019). Theoretical relation between axon initial segment geometry and excitability. bioRxiv, 834671.