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Published July 1, 2018 | Version Pre-print
Journal article Open

Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries

Authors/Creators

  • 1. Department of Urology and Transplant Surgery, Beaumont Hospital, Dublin, Ireland
  • 2. Centre for Applied Biomedical Engineering Research, School of Engineering, Bernal Institute and the Health Research Institute, University of Limerick, Limerick, Ireland
  • 3. Department of Gender Reassignment Surgery, University of Essen, Essen, Germany

Description

Despite the preventable iatrogenic morbidities and associated medicolegal costs
secondary to urethral catheterisation related injuries, few studies examine
mechanisms to prevent such incidences. Of those studies that examine mechanisms,
none are based on data obtained from testing of human urethras. This study
characterises the relevant mechanics of human urethral tissue in order to further
develop mechanisms to prevent urinary catheter related injuries. This study
demonstrates that human male urethra injury occurs at an external urethral diametric
stretch ≥1.26 or with balloon inflation pressures ≥120kPa. Iatrogenic injuries will
therefore continue to occur as contemporary catheters routinely generate significantly
higher inflation pressures. Safety mechanics must therefore be introduced using
findings derived from appropriate models such as those outlined in this study.

Files

Davis and Cunnane et al 2018 Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries.pdf

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Additional details

Funding

European Commission
LAF-GRAFT - An Investigation into the viability of employing lipoaspirate fluid as a cellular source in the production of small diameter tissue engineered vascular grafts 708867