Published November 1, 2019 | Version v1

In silico prediction of high-resolution Hi-C interaction matrices (part II)

  • 1. Wisconsin Institute for Discovery
  • 2. Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison

Description

The uploaded files are source datasets for the HiC-Reg approach. HiC-Reg is a regression based method that predict contact counts from one-dimensional regulatory signals such as epigenetic marks and regulatory protein binding. See more details here (https://github.com/Roy-lab/HiC-Reg). There are a total of six files in this dataset: Data.tgz, Gm12878.tgz, Hmec.tgz, K562.tgz, Huvec.tgz and Nhek.tgz. The Data.tgz include predictions and other downstream analysis such as feature importance analysis, significant interaction calling, and data files for select figures. The Gm12878.tgz, K562.tgz, Huvec.tgz, Hmec.tgz and Nhek.tgz contain trained models, predictions, feature files for two chromosomes for in each cell line.

This is part II of the dataset which contains K562.tgz and Huvec.tgz.

Notes

This work is supported by the National Institutes of Health (NIH), BD2K grant U54 AI117924 and NIH R01-HG010045-01.

Files

Files (35.3 GB)

Name Size
md5:0fdef80fbfc17a4d75be9b1912294bd6
16.0 GB Download
md5:effbfc8d8294f0f18035ebbea0862821
19.4 GB Download