Published November 1, 2019 | Version v1

In silico prediction of high-resolution Hi-C interaction matrices (part I)

  • 1. Wisconsin Institute for Discovery
  • 2. Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison

Description

The uploaded files are source datasets for the HiC-Reg approach. HiC-Reg is a regression based method that predict contact counts from one-dimensional regulatory signals such as epigenetic marks and regulatory protein binding. See more details here (https://github.com/Roy-lab/HiC-Reg). There are a total of six files in this dataset: Data.tgz, Gm12878.tgz, Hmec.tgz, K562.tgz, Huvec.tgz and Nhek.tgz. The Data.tgz include predictions and other downstream analysis such as feature importance analysis, significant interaction calling, and data files for select figures. The Gm12878.tgz, K562.tgz, Huvec.tgz, Hmec.tgz and Nhek.tgz contain trained models, predictions, feature files for two chromosomes for in each cell line.

This is part I of the dataset which contains Gm12878.tgz and Hmec.tgz.

Notes

This work is supported by the National Institutes of Health (NIH), BD2K grant U54 AI117924 and NIH R01-HG010045-01.

Files

Files (40.3 GB)

Name Size
md5:c5502ca9c58a6c113f5ffeeebed3a8dd
25.0 GB Download
md5:043c6e50dc45a429afdefe4e4b18eeb7
15.3 GB Download