Published October 30, 2019
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Supplementary Material for "General Principles for Yield Optimization of Nucleoside Phosphorylase-Catalyzed Transglycosylations"
Description
This is the supplementary material for our publication "General Principles for Yield Optimization of Nucleoside Phosphorylase-Catalyzed Transglycosylations".
The .pdf file contains the supplementary information: Author Contributions, Conflict of Interest, Sample analysis by HPLC, Table S1 and a suggested workflow for NPase-catalyzed nucleoside synthesis.
The .xlsx file contains an implementation of the simplified formula for yield prediction (equation (4) ), using previously reported thermodynamic data (10.5281/zenodo.3459298).
The Python code and all data calculated from numerical solutions of the system of equilibrium constraints is available elsewhere (10.5281/zenodo.3522588).
Notes
This work was supported by the German Research Foundation (DFG) under Germany´s Excellence Strategy – EXC 2008/1– 390540038 (UniSysCat), and by the Einstein Foundation Berlin (ESB) - Einstein Center of Catalysis (EC2) and the Deutsche Forschungsgemeinschaft (DFG), grant number 392246628.
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Supplementary Information Transglycosylation Kaspar & Giessmann et al. ASC.pdf
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Related works
- Is supplemented by
- 10.5281/zenodo.3522588 (DOI)