Published October 24, 2019
| Version v1
Dataset
Open
USP5 Ubiquitin-Rhodamine110 Catalytic Activity Assay
Authors/Creators
- 1. University of Toronto, Structural Genomics Consortium
Description
A ubiquitin-rhodamine110 assay was used to determine if ZnF-UBD ligands antagonize USP5 deubiquitinase (DUB) activity
Notes
Funding acknowledgement: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.