Published September 25, 2019 | Version v1
Journal article Open

The relationship between people with toxoplasmosis and changes in thyroid hormone levels between 2017 and 2018, Khartoum, Sudan

  • 1. Department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Science, ALzaiem Alazahari University, Khartoum North, Sudan
  • 2. Department of Parasitology and Medical Entomology, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan
  • 3. M.Sc. student, department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Science, Alzaiem Alazahari University, Khartoum North, Sudan
  • 4. Department of Microbiology and Immunology, Faculty of Medical Laboratory Science, Alzaiem Alazahari University, Khartoum North, Sudan
  • 5. Department of Parasitology and Medical Entomology, Faculty of Medical Laboratory Science, Alzaiem Alazahari University, Khartoum North, Sudan

Description

Toxoplasma gondii parasites are capable to affect any organs and glands in human and this causes the appearance of different clinical sign. The present study was performed to examine the effect of toxoplasmosis infection on thyroid hormone levels among Sudanese patients in Khartoum State that help in early diagnosis and treatment and there is no data in Sudan. The study was cross section design which was conducted among 100 patients including males and females (pregnant and non pregnant) with toxoplasmosis. Enzyme Linked Immunosorbent Assay (ELISA) was used to detect the presence of anti Toxoplasma IgM and IgG antibodies and detect the levels of thyroid hormones. The study showed Toxoplasma antibody types in relation to patient gender, especially 61.1% of IgG was critical to females including pregnant and non pregnant and 38.8% of the same type of antibodies within males and 6.6 % of IgM was critical to females including pregnant and non pregnant. Also 2.2% of the same type of antibodies within males and 54.4% was abnormal thyroid hormones levels.  34.4% was critical to females including pregnant and non pregnant and 20.0% in males. The prevalence of abnormal biochemical thyroid function reported here was substantial. A thyroid function hormones level assessed by using ELISA technique among patients with toxoplasmosis is useful.

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