Journal article Open Access
Ibrahim Mohammed Eisa; Tayseer Elamin Mohamed Elfaki; Al-Jaili Mohammed Ahmed; Maaley Mohammed Khery; Rayan Mahgoub Ali Adam; Mohammed Ahmed Ibrahim Holie; Mohamed Mobarak Elbasheir
Toxoplasma gondii parasites are capable to affect any organs and glands in human and this causes the appearance of different clinical sign. The present study was performed to examine the effect of toxoplasmosis infection on thyroid hormone levels among Sudanese patients in Khartoum State that help in early diagnosis and treatment and there is no data in Sudan. The study was cross section design which was conducted among 100 patients including males and females (pregnant and non pregnant) with toxoplasmosis. Enzyme Linked Immunosorbent Assay (ELISA) was used to detect the presence of anti Toxoplasma IgM and IgG antibodies and detect the levels of thyroid hormones. The study showed Toxoplasma antibody types in relation to patient gender, especially 61.1% of IgG was critical to females including pregnant and non pregnant and 38.8% of the same type of antibodies within males and 6.6 % of IgM was critical to females including pregnant and non pregnant. Also 2.2% of the same type of antibodies within males and 54.4% was abnormal thyroid hormones levels. 34.4% was critical to females including pregnant and non pregnant and 20.0% in males. The prevalence of abnormal biochemical thyroid function reported here was substantial. A thyroid function hormones level assessed by using ELISA technique among patients with toxoplasmosis is useful.