Dataset Open Access

ROS-Specific Huntingtin Interactions: Chromatin retention assay with huntingtin fragments containing PBM3

Maiuri, Tamara; Truant, Ray

Huntingtin amino acids 1790-1798 make up a potential PAR binding motif (PBM3). Two huntingtin fragments (1208-1810 and 1775-2413) were tested for chromatin retention upon oxidative stress.

This work is funded by the HDSA Berman/Topper HD Career Development Fellowship.
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Publication date:
September 24, 2019
DOI:
10.5281/zenodo.3459660

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10.5281/zenodo.3459660

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Keyword(s):
huntingtin Huntington's disease ROS reactive oxygen species oxidative stress poly ADP ribose chromatin retention assay
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