Relationship Between Lipid Profile And Inflammatory Markers In Type 2 Diabetes Mellitus
Authors/Creators
- 1. KSHEMA, Nitte (Deemed to be University), Deralakatte, Mangalore, India.
Description
Inflammatory response is one of the main causative factors for the aetiology of Type 2 Diabetes mellitus. Diabetes mellitus may play a crucial role in the pathogenesis of the disease and is associated with dyslipidaemia. The study aims to determine the relationship between lipid profile and inflammatory markers in type 2 diabetes mellitus. A total of 140 study subjects were recruited in the study in which 70 were non-diabetic subjects served as control and 70 were known cases of type 2 diabetes mellitus between the age group 30-60 years. FBS, HbA1C, Lipid profile, CRP and Interleukin 6 were estimated. C - reactive protein and Interleukin 6 levels of diabetic group showed a significant correlation with Total Cholesterol, Triglyceride, LDL cholesterol whereas a significant negative correlation was observed with HDL-Cholesterol in type 2 diabetes mellitus patients. The study concludes that there is a relationship between the lipid profile and inflammatory markers in T2DM and suggests a significant role of the inflammatory markers in the pathogenesis of dyslipidaemia in diabetes
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