Journal article Open Access

FORMULATION AND EVALUATION OF BACLOFEN EXTENDED RELEASE TABLETS.

Suresh Kumar .P*, Madhva Rao .S .Jagannath Patro.V, Vanitha .S .Bindhu .T, Sunitha .CH

The aim of the present study was to develop Extended release formulation of Baclofen to maintain constant therapeutic levels of the drug for over 12 hrs. Guar gum, sodium alginate and carbopol 940 were employed as polymers. All the formulations were passed various physicochemical evaluation parameters and they were found to be within limits. Whereas from the dissolution studies it was evident that the formulation (F6) showed better and desired drug release pattern i.e., 96.32% in 12 hours. It contains the sodium alginate as Extended release material. It followed Zero order release kinetics mechanism.

Files (951.9 kB)
Name Size
190803.pdf
md5:bad42b68a580170cb241c22e9123eb0f
951.9 kB Download
14
13
views
downloads
All versions This version
Views 1414
Downloads 1313
Data volume 12.4 MB12.4 MB
Unique views 1414
Unique downloads 1212

Share

Cite as