Recent Approaches in Computational Drug Delivery System
Authors/Creators
- 1. M Pharm Student, Department of Pharmaceutics, SSR College of Pharmacy, Sayli Road, Silvassa, Union Territory of Dadra and Nagar Haveli, India
- 2. Assistant Professor, Department of Pharmaceutics, SSR College of Pharmacy, Sayli Road, Silvassa, Union Territory of Dadra and Nagar Haveli, India
- 3. M Pharm Student, Department of Pharmacology, SSR College of Pharmacy, Sayli Road, Silvassa, Union Territory of Dadra and Nagar Haveli, India
Description
Systematizing a state-of-the-art drug delivery (DD) system which can deliver Active Pharmaceutical Ingredient (API) in safe and efficacious way is a premium process which requires years of development. Computational Drug Delivery is a unique way which utilizes computer aided simulations of models based on the Computational Fluid Dynamics (CFD), Volume of Fluid (VOF) technique and Molecular Dynamics (MD) combined with medical imaging techniques such as Computerized Axial Tomography (CAT) Scan, Magnetic Resonance Imaging (MRI) and Ultrasound to simulate in vivo conditions for better understanding of the drug delivery systems. This review article aims at elaborating the distinct approaches of Computational Drug Delivery in nanoparticulate, Microsphere Drug Delivery, liposomal Drug Delivery, brain specific, liver specific, tumour specific targeting along with optimization in traditional methods. Computational drug delivery approaches in the pharmaceutical sciences have the main goal of rational drug discovery and development.
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References
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