Journal article Open Access

HEREDITARY ANGIOEDEMA: AN UNUSUAL CAUSE OF VOMITING: A CASE REPORT

S.Ghani , I.Errabih , N. Benzzoubeir , F.Souidine and L. Ouazzani.

Hereditary angioedema (HAE) is part of the bradykininangioedema. It is a rare and life-threatening disease that affects about 1 in 10,000 to 50,000 people. It is a genetic disease; associated with an abnormality on the C1-inhibitor gene that leads to a deficiency of C1-inhibitor (INH), this deficiency results in uncontrolled activation of the contact system of coagulation and the classical complement pathway, resulting in excessive production of bradykinin. This disease is manifested by acute attacks of intermittent cutaneous or mucosal edema. The angioedema of the digestive tract or abdominal viscera causes intense pain, often accompanied by vomiting related to edematous intestinal obstruction, these edemas usually evolve in a few hours and persist for a few days. These crises are unpredictable and can be very serious if they affect the respiratory sphere. In this \\\"development\\\", after a brief review of the pathophysiology of angioedema (AE), we will detail the clinical manifestations, diagnosis and management of HAE, with a particular focus on new therapeutic agents and treatment modalities.

Files (309.8 kB)
Name Size
1.pdf
md5:09d10a9664c970d9ab8559decbf24ece
309.8 kB Download
2
3
views
downloads
All versions This version
Views 22
Downloads 33
Data volume 929.4 kB929.4 kB
Unique views 22
Unique downloads 22

Share

Cite as