Published August 20, 2015
| Version v1
Dataset
Open
Immune repertoire profiling reveals that clonally expanded B and T cells infiltrating diseased human kidneys can also be tracked in the blood
Creators
- 1. Ludwig Boltzmann Institute for Experimental and Clinical Traumatology Linz, Austria
- 2. Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg, Austria
- 3. Department of Internal Medicine III, KH Elisabethinen Linz and Medical University of Vienna
- 4. Department of Molecular Biology, University of Salzburg, Salzburg, Austria
Description
Recent advances in high-throughput sequencing allow for the competitive analysis of the human B and T cell immune repertoire. In this study we compared Immunoglobulin and T cell receptor repertoires of lymphocytes found in kidney and blood samples of 10 patients with various renal diseases based on next-generation sequencing data.
Files
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(17.2 GB)
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