Published March 29, 2019 | Version v1

Enrichment of gene sets altered in dram1 mutant zebrafish larvae

  • 1. Institute of Biology, Leiden University

Description

Enrichment of gene sets altered in dram1 mutant zebrafish larvae.

A. Gene Ontology categories significantly over and underrepresented in the significant genes differentially regulated between dram1∆19n/∆19n PBS-injected mutants compared to dram1+/+ larvae.

B. Gene sets from the MSigDB C2 database significantly positively correlated to the dram1∆19n/∆19n mutants transcriptome compared to dram1+/+ larvae.

C. Gene sets from the MSigDB C2 database significantly negatively correlated to the dram1∆19n/∆19n mutants transcriptome compared to dram1+/+ larvae.

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Additional details

Funding

European Commission
Inflammafish - Cross-talk between inflammation and autophagy in tuberculosis 655424
European Commission
LEaDing Fellows - LEaDing Fellows 707404
European Commission
FISHFORPHARMA - Training Network on Zebrafish Infection Models for Pharmaceutical Screens 289209
Dutch Research Council
Novel immunomodulatory drugs for tuberculosis treatment. 2300182443