ANALYSIS OF DRUG DELIVERY SYSTEM IN IMPLANT DENTISTRY

Infections associated with implantable devices, also known as biomaterial-associated infections (BAIs) pose a serious problem in contemporary regenerative medicine and traumatology. In recent years, the number of procedures which make use of different biomaterials in oral and maxillofacial surgery (OMFS) have significantly increased. The basic aim of the study is to analyze the drug delivery system in implant dentistry. This meta-analysis was conducted in Demontmorency College of Dentistry, Lahore during 2018. A customized electronic search for published literature of last ten years was done and all the articles on dental implants as drug carriers were carefully analyzed. The trend of research on dental implants as drug carriers has been increasing over last few decades as demonstrated in the graph below. In a recent study, a biodegradable nanoporous bioceramic system was used as a highly bioresorbable matrix for drug delivery. This study emphasized the efficacy of hydroxyapatite-based material having interconnected nanoporosity as a vehicle for a therapeutic agent. It is concluded that Dental implants can be used successfully as drug carriers. Most successfully delivered and tested therapeutic agents via dental implants are bone morphogenetic proteins.