PHARMACOLOGICAL SCREENING OF ANTI DIABETIC ACTIVITY OF AQUEOUS EXTRACT OF LEAVES AND FLOWERS OF BUTEA MONOSPERMA
Authors/Creators
- 1. * 1 Assistant Professor, Vision College of Pharmaceutical Sciences & Research, Boduppal, Hyderabad 500092, Telangana, INDIA. 2 Doctor in Pharmacy, C L Baid Mehta College of Pharmacy, Chennai, INDIA. 3 B. Pharmacy, Vision College of Pharmaceutical Sciences & Research, Hyderabad, Telangana, INDIA.
Description
ABSTRACT
Butea Monosperma is an Indian traditional plant used in treating diabetes. Butea Monosperma posses strong antioxidant, α-glucosidase inhibitory activity. And the aqueous extract of the flower also have the chemical constituents which are responsible for having free radical scavenging nature. The Phytochemical screening of the aqueous extract of flower of Butea Monosperma showed the positive results for Flavonoids, Glycosides, Carbohydrates and Amino Acids. From The Phytochemical study we found that the extract has the antioxidant properties. By this Result we extended our work by administering in diabetes induced SD Rats to check whether it has any antidiabetic activity or not. So, after treating the diabetic rats for 14days with our extract we found that the blood glucose levels got decreased when we compared it with the first day of glucose levels. Hence, we confirmed that the aqueous extract of the flower of Butea Monosperma has the antidiabetic activity.
KEYWORDS: Diabetic, Butea Monosperma, Pharmacological Activity, Alloxan, Aqueous Extract.