Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of Cardiometabolic phenotypes
Creators
- 1. Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Canada
Description
GWAS summary statistics for 2083 circulating-miRNA as described in:
Genome-wide identification of circulating-miRNA expression quantitative trait loci
reveals the role of several miRNAs in the regulation of Cardiometabolic phenotypes
[Cardiovascular Research 2019; DOI: 10.1093/cvr/cvz030]
Each file is named as "miRNA Name.mirqtls.gz" and has the following columns:
Chr: Chromosome of the variant
bp: Position of the variant in GRCh37 coordinates
SNP: rsid
A1: Reference allele on the forward strand
A2: Alternate allele on the forward strand
freq: Frequency of reference allele
b: Estimated effect size (beta regression coefficient) of reference allele
se: Estimated standard error of beta
p: p-value (significance of estimated beta)
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