Non-Invasive Assessment of Coronary Stenoses and Comparison to Invasive Techniques: a proof-of-concept study
Authors/Creators
- 1. Unit of Medical Technology and Intelligent Information Systems, Dept. of Materials Science and Engineering, University of Ioannina, GR 45110, Greece
- 2. Dept. of Interventional Cardiology at the Heart Institute (InCor) University of Sao Paulo Medical School 627, Sao Paulo, Brazil
- 3. Michaelideion Cardiac Center,Dept. of Cardiology in Medical School, University of Ioannina,
- 4. Unit of Medical Technology and Intelligent Information Systems, Dept. of Materials Science and Engineering, University of Ioannina, Dept. of Biomedical Research, FORTH-IMBB, Ioannina, GR 45110, Greece
Description
Coronary Computed Tomography Angiography (CCTA) has gained substantial ground in everyday clinical practice due to its non-invasive nature. In this work we present a noninvasive method to assess the hemodynamic significance of coronary stenoses using only CCTA images. Two female patients were subjected to Invasive Coronary Angiography, Virtual Histology IVUS and CCTA. The same arterial segment was reconstructed in 3D using the proposed method as well as two already validated 3D reconstruction methods using the aforementioned invasive techniques. The lumen diameter reduction (%) and the minimum lumen diameter (mm) were calculated for all cases and a relative error <5% was observed between all three techniques.