Published January 28, 2019
| Version v1
Dataset
Open
Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis
Creators
- 1. The Francis Crick Institute
- 2. Department of Veterans Affairs Medical Center
Description
Data on uptake and metabolism of all 20 amino acids by Mycobacterium tuberculosis H37Rv (20 amino acids uptake.zip), shown in Figure 2.
Data on kinetics of labelling on 15N-Asp (15N Asp.zip), shown in Figure 4g and h.
Data on kinetics of labelling on 15N2-Asn (15N Asn.zip), shown in Figure 4g and h.
Data on kinetics of labelling on 15N-Glu (15N Glu.zip), shown in Figure 4g and h.
Data on kinetics of labelling on 15N2-Gln (15N Gln.zip), shown in Figure 4g and h.
Data on kinetics of labelling on 15N-NH4+ (15N NH4+.zip), shown in Figure 4g and h.
Data on position specific labelling with Asn and Gln (PIL.zip), shown in Figure 4b to f.
Data on co-metabolism of Glu/Gln and Asp/Asn (co-metabolism.zip), shown in Figure 5.
Notes
This work was primarily supported by a Wellcome Trust New Investigator Award (104785/B/14/Z) to L.P.S.C. The L.P.S.C. lab is also funded by the Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001060), the UK Medical Research Council (FC001060), and the Wellcome Trust (FC001060).
Files
15N Asn.zip
Files
(8.0 GB)
| Name | Size | Download all |
|---|---|---|
|
md5:82681959f9cd76fc5b9353645db02559
|
1.4 GB | Preview Download |
|
md5:21a91e88962db0d3f7264acbc5bf194c
|
1.0 GB | Preview Download |
|
md5:edc0149fcdc13829c98da03a7c76677d
|
1.6 GB | Preview Download |
|
md5:3e3e0ebe7ae2dd0ab1163c09e5ad729f
|
987.9 MB | Preview Download |
|
md5:96109d38f64db623b957328826e02783
|
570.5 MB | Preview Download |
|
md5:bfd4dbf314cf1e452ca52bf53f33faef
|
1.2 GB | Preview Download |
|
md5:381397bcad09d4f210edce594b6e0bdc
|
495.4 MB | Preview Download |
|
md5:09ce592e5aec363f59e241b5656be1d8
|
729.0 MB | Preview Download |
Additional details
Funding
- Uncovering Nutrient Acquisition and Metabolism in Mycobacterium tuberculosis. 104785
- Wellcome Trust