Journal article Open Access

FAST DISSOLVING SYSTEMS – AN ALTERNATIVE APPROACH FOR ENHANCED THERAPEUTIC ACTION

R. Santosh Kumar*, T. Naga Satya Yagnesh

From the past years the advancement of pharmaceutical technology has presented the change of dosage forms for patients who may have difficulty in swallowing of conventional tablets. The systems which disintegrate and release the active ingredient quickly and that do not require water to aid swallowing are fast dissolving drug delivery systems (FDDDSs). Amid the FDDDS, the fast disintegrating tablets (FDTs) are the attendant defensible form of drug delivery system because of its convenience of self-administration and compactness. The traditional capsules and tablets administration has shown difficulty in swallowing for pediatric, geriatric, and uncooperative patients. The basic creep up on used in blooming of FDT is the use of superdisintegrants which bestow immediate disintegration and thereby releasing the drug in saliva. Oral administration of bitter drugs with an acceptable degree of palatability can be attained by taste masking. These promulgation reviews the applications and technologies intricate in the formulation of FDDDS especially focused on FDTs.

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