Journal article Open Access
Gopichand Bhoi*, Vishal Lad, Vijay Shastry
Cancer is an abnormal growth of cells which tends to proliferate in an uncontrolled way and in some cases to spread. Many anticancer drugs are available in market with a lot of side-effects. So our objective is to introduced a drug “sweet wormwood” (Artemisia annua) that is 1,000 times better than chemotherapy. In chemotherapy, for every 5 cancer cells 1 normal cell may be destroyed but a recent study found that wormwood can kill up to 12,000 cancer cells for every 1 healthy cell it may affect. The active ingredient that makes sweet wormwood such a cancer healer is artemisinin. The special super concentrated compound of wormwood and iron can target cancer cells while leaving healthy cells alone. The compound is specially effective in combating breast cancer. Wormwood and iron together is said to act as a “Trojan horse”, creating a literal “time bomb” for cancer cells. Cancer cells are not as successful as healthy cell in disposing of free floating iron molecules. This weakness causes the presence of iron in general to create stressful environment for cancer cells. This compound works on a general property of cancer cells, their high iron content. Breast cancer cells in particular can sometimes contain up to 15 times more iron receptors than surrounding cells, which is why this iron-artemisinin duo may have an even more profound effect on breast cancer. “Artemisinin reacted with iron to form free radicals which cause cell death”. The artemisinin and its derivatives are toxic to the malarial parasites at nanomolar concentrations, causing specific membrane structural changes in the erythrocyte stage that kills the parasites. The WHO recommends artemisinin- based combination therapies as first line treatment for P. falciparum malaria because it reacts with the high levels of iron in the parasites to produced the free radicals which then destroy the cell walls of malarial- parasite. Act as anti malarial, anti parasitic, anti fungal, anti microbial, anti-inflammatory.