Antimicrobial Activity of Swietenia mahagoni L (Leaf) Against Various Human Pathogenic Microbes

Different organic and aqueous extracts of leaves of Swietenia mahagoni L (Meliaceae) were screened for their antimicrobial activity against seven human pathogenic bacteria and two fungal strains by plate hole diffusion assay to determine the growth inhibition of microorganisms. The medicinal plant appear to have a broad antimicrobial activity spectrum, they could be useful in antiseptic, disinfectant and other antimicrobial agent formulation. Among the various micro organisms, the methanolic extract was more active against Bacillus subtilis, Klebsiella pneumoniae and E. coli. In antifungal activity of the methanolic extract shows positive results for fungus.