Published November 28, 2018
| Version v1
Dataset
Open
Size-exclusion chromatography (SEC) - multi-angle light scattering (MALS) analysis of HTT and HTT-HAP40 complex samples – 2018/11/27
Authors/Creators
- 1. Structural Genomics Consortium, University of Toronto
Description
Project - Huntingtin structure-function open lab notebook.
Experiment - Size-exclusion chromatography (SEC) - multi-angle light scattering (MALS) analysis of HTT and HTT-HAP40 complex samples – 2018/11/27. To investigate how monodispersity of HTT and HTT-HAP40 samples.
Notes
Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome. Thanks to OICR for access to their MALS equipment and Ahmed Aman for his assistance in running experiments.